top of page

Antibiotics and Your Microbiome: A Delicate Balance

Writer's picture: Joe MontemoranoJoe Montemorano


Hello, health enthusiasts! Today, we're diving into the fascinating world of antibiotics and our microbiome. Buckle up for a journey through the microscopic universe that lives within us!

We Are Not Alone!

Did you know that you're never truly alone? That's right - your body is home to a bustling metropolis of microorganisms! This community, known as the human microbiota, consists of 10-100 trillion symbiotic microbial cells. These tiny tenants include bacteria, fungi, and parasites that live on or within our bodies. They outnumber our cells by a whopping 10 to 1!

But here's where it gets mind-blowing: your gut alone hosts about 500 species of bacteria. And get this - the genome of your gut bacteria outnumbers your human genome by 100 to 1! Talk about a crowded house!

Antibiotics to the Rescue!

Now, let's talk about the superheroes of the medical world - antibiotics! These wonder drugs have been saving lives since their discovery. In the U.S. alone, antibiotics save about 200,000 lives annually and have added 5-10 years to our life expectancy. That's no small feat!

To put this into perspective, let's look at pneumonia. In 1935, the survival rate for pneumonia was a mere 20%. Fast forward to 1964, and thanks to antibiotics, that rate skyrocketed to 85%! Now that's what we call a medical miracle!

The Flip Side: Antibiotic Side Effects

But as with any superhero, antibiotics have their kryptonite too. Here are the top 5 side effects to watch out for:

  1. Digestive Issues: Nausea, vomiting, diarrhea, and abdominal pain are common unwelcome guests.

  2. Allergic Reactions: These can range from mild rashes to severe, life-threatening anaphylaxis.

3. Fungal Infections: When antibiotics disrupt good bacteria, opportunistic fungi like Candida can throw a party in your body.

4. Photosensitivity: Some antibiotics can make your skin extra sensitive to sunlight. Hello, unexpected sunburn!

5. Blood Reactions: Certain antibiotics can affect blood cell counts, leading to leukopenia/thrombocytopenia.

The Compliance Conundrum

Now, here's where things get tricky. Many people don't take their antibiotics as prescribed. This is what we call "antibiotic non-compliance," it's a bigger problem than you might think.

  • Studies show up to 32.1% of patients don't follow their antibiotic regimen correctly. Yikes!

  • But here's an interesting tidbit: 77% of patients completed their course of antibiotics when their GI side effects were controlled. This suggests that managing those pesky side effects could improve compliance.

The Resistance Rebellion

  • Antibiotic resistance. Here's where things get serious.

  • Antibiotic resistance is a growing global threat. It's responsible for approximately 1.27 million deaths annually and contributes to 4.95 million deaths worldwide.

  • That's not all - it could result in an additional $1 trillion in healthcare costs by 2050!

  • But how does this happen?

  • Well, bacteria are clever little creatures. They can develop resistance through mutations or by acquiring resistance genes from other bacteria. It's like they're constantly upgrading their defense systems!

The Probiotic Solution

So, what can we do about all this? Enter probiotics - the friendly bacteria that could be our secret weapon in the fight against antibiotic side effects and resistance.

Here's how probiotics can help:

  1. Reduce Antibiotic-Associated Diarrhea: Probiotics can decrease the risk of this common side effect by up to 51%. That's a game-changer for compliance!

  2. Mitigate Other GI Side Effects: Say goodbye to bloating, gas, and abdominal discomfort. Probiotics help alleviate these issues, making it easier to stick to your antibiotic regimen.

  3. Restore Gut Microbiome Balance: Probiotics help repopulate your gut with beneficial bacteria, getting your microbiome back in balance faster.

  4. May Reduce Antibiotic Resistance: By supporting gut health and potentially reducing the need for repeated antibiotic courses, probiotics could indirectly help slow the development of antibiotic-resistant bacteria.

5. Improve Overall Treatment Outcomes: With reduced side effects and better compliance, you're more likely to complete your full course of antibiotics. This is crucial for effectively treating infections and preventing the development of antibiotic-resistant strains.

6. Reduce Vaginal Side Effects: Probiotics may help reduce the chance of vaginal yeast infections, which occur in about 25% of women after antibiotic use.

The Bottom Line

Antibiotics are incredible, life-saving drugs. But like any powerful tool, they need to be used responsibly. By understanding the importance of compliance, the threat of resistance, and the potential of probiotics, we can make the most of these medical marvels while protecting our microscopic allies. Remember, your microbiome is your friend. Treat it well, and it will return the favor! Stay healthy, stay informed, and keep those good bacteria thriving!

Why This Pharmacist Recommends Florajen Refrigerated Probiotics

As a pharmacist with over 40 years of experience and the owner of RxHealthHabits, I'm often asked about the best probiotics to take, especially when using antibiotics. My view on probiotics is similar to what my friend Frankie, a New York pizzeria owner, says about pizza: "Forget about it! After you try the best, you'll be done with the rest!"

Today, I want to share why I recommend Florajen's line of refrigerated probiotics. Here are three key reasons:

  1. Cold Chain Commitment: Florajen keeps its probiotics refrigerated from manufacturing to delivery. This is crucial because probiotics are live bacteria that die off faster at room temperature. By maintaining a cold chain, Florajen ensures maximum potency and effectiveness. Just as you wouldn't leave a pizza out overnight and expect it to taste fresh, probiotics need proper storage to maintain their quality.

  2. High Cell Counts: Thanks to their refrigeration process, Florajen probiotics maintain high numbers of live cultures through their expiration date. This means you're getting billions of beneficial bacteria in each dose, which is especially important when taking antibiotics. It's like getting a pizza loaded with toppings - you're getting more of what you want and need.

  3. Targeted Formulas: Florajen offers specific formulations for different needs - like digestive health, women's health, and children's health. This allows for more tailored probiotic support during antibiotic treatment. It's like being able to customize your pizza to suit your exact tastes and dietary needs.


Remember, when you're prescribed antibiotics, ask your pharmacist about Florajen refrigerated probiotics. They're an effective way to support your gut health before, during, and after antibiotic therapy. Just as Frankie takes pride in serving the best pizza,

I take pride in recommending the best probiotics to my patients.

References:

  1. Francino, M.P. (2016). Antibiotics and the Human Gut Microbiome: Dysbioses and Accumulation of Resistances. Frontiers in Microbiology, 6, 1543.

  2. Ventola, C.L. (2015). The Antibiotic Resistance Crisis: Part 1: Causes and Threats. Pharmacy and Therapeutics, 40(4), 277-283.

  3. Hempel, S., et al. (2012). Probiotics for the prevention and treatment of antibiotic-associated diarrhea: a systematic review and meta-analysis. JAMA, 307(18), 1959-1969.

  4. O'Neill, J. (2016). Tackling drug-resistant infections globally: Final report and recommendations. Review on Antimicrobial Resistance.

  5. McFarland, L.V. (2015). Probiotics for the Primary and Secondary Prevention of C. difficile Infections: A Meta-analysis and Systematic Review. Antibiotics, 4(2), 160-178.


At RxHealthyHabits, our goal is to teach people how to be healthy using natural methods like diet, exercise, and overall lifestyle changes. We are passionate about helping you develop “self-health care” (developing healthy lifestyle habits) so you don’t have to rely only on “sick care”(medical and pharmacy therapies). We are here to help you on your journey. Reach out to us.

Contact us today, we love to hear from our readers!

Follow us on your favorite(s) social media platforms.

Links:

Do you have questions about health? Are you interested in appearing as a guest in our video series? We would love to have you on a video or podcast. Contact us 

 
 
 

Comments


Have a question, feedback, or want to contribute?

Get in touch!

bottom of page